High Impact Journal from Malaria Portal

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MJ Ponsford et al. Sequestration and Microvascular Congestion Are Associated With Coma in Human Cerebral Malaria. J Infect Dis

Sun, 2012-12-30 06:00
The pathogenesis of coma in severe Plasmodium falciparum malaria remains poorly understood. . . .
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MJ Ponsford et al. Sequestration and Microvascular Congestion Are Associated With Coma in Human Cerebral Malaria. J Infect Dis

Sun, 2012-12-30 06:00
The pathogenesis of coma in severe Plasmodium falciparum malaria remains poorly understood. . . .
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M Gwamaka et al. Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia. Malar J

Sun, 2012-12-30 06:00
ABSTRACT: BACKGROUND: Levels of complement regulatory proteins (CrP) on the surface of red blood cells (RBC) decrease during severe malarial anaemia and as part of cell ageing process. . . .
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D é et al. [Home caregiver in Senegal]. Rev Infirm

Sun, 2012-12-30 06:00
Kiné Sow is a home caregiver in the Senegalese village of Ndienné. . . .
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C Ayres et al. Comparative genomics of the anopheline glutathione s-transferase epsilon cluster. PLoS One

Sat, 2012-12-29 06:00
Enzymes of the glutathione S-transferase (GST) family play critical roles in detoxification of xenobiotics across many taxa. . . .
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A Nacer et al. clag9 Is Not Essential for PfEMP1 Surface Expression in Non-Cytoadherent Plasmodium falciparum Parasites with a Chromosome 9 Deletion. PLoS One

Sat, 2012-12-29 06:00
The expression of the clonally variant virulence factor PfEMP1 mediates the sequestration of Plasmodium falciparum infected erythrocytes in the host vasculature and contributes to chronic infection. . . .
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J Zhao et al. Indicators measuring the performance of malaria programs supported by the global fund in Asia, progress and the way forward. PLoS One

Sat, 2012-12-29 06:00
In 2010, the Global Fund provided more than 75% of external international financing for malaria control. . . .
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J ález et al. [Malaria imported into Spain.] Rev Clin Esp

Sat, 2012-12-29 06:00
[No abstract]
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PM Jones et al. The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations. PLoS One

Sat, 2012-12-29 06:00
Malaria caused by several species of Plasmodium is major parasitic disease of humans, causing 1-3 million deaths worldwide annually. . . .
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AP ário et al. IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection. J Immunol

Sat, 2012-12-29 06:00
Infection with the malaria parasite, Plasmodium, is characterized by excessive inflammation. . . .
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T Beghyn et al. Drug-to-Genome-to-Drug, Step 2: Reversing Selectivity in a Series of Antiplasmodial Compounds. J Med Chem

Sat, 2012-12-29 06:00
In a recent paper, we have described the discovery of antimalarial compounds derived from tadalafil, thanks to a Drug-to-Genome-to-Drug approach1 (J. . . .
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E Yalcindag et al. Multiple independent introductions of Plasmodium falciparum in South America. Proc Natl Acad Sci U S A

Fri, 2012-12-28 06:00
The origin of Plasmodium falciparum in South America is controversial. . . .
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N Frahm et al. Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine. J Clin Invest

Fri, 2012-12-28 06:00
Recombinant viruses hold promise as vectors for vaccines to prevent infectious diseases with significant global health impacts. . . .
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AI ón et al. Antimalarial natural products drug discovery in Panama. Pharm Biol

Wed, 2012-12-26 06:00
Context: Malaria is still a major public health problem. . . .
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MA el-Hazmi et al. Sickle cell disease in Middle East Arab countries. Indian J Med Res

Wed, 2012-12-26 06:00
The sickle cell (HbS) gene occurs at a variable frequency in the Middle Eastern Arab countries, with characteristic distribution patterns and representing an overall picture of blood genetic disorders in the region. . . .
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GD Oliveira et al. Epithelial Nitration by a Peroxidase/NOX5 System Mediates Mosquito Antiplasmodial Immunity. Science

Fri, 2012-01-27 06:00
Plasmodium ookinetes traverse midgut epithelial cells before they encounter the complement system in the mosquito hemolymph. . . .
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