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B Zelman et al. Costs of Eliminating Malaria and the Impact of the Global Fund in 34 Countries. PLoS One

High Impact Journal from Malaria Portal - 31 December 2015 - 12:00am
International financing for malaria increased more than 18-fold between 2000 and 2011; the largest source came from The Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund). . . .
Categories: malaria news feeds

AJ Arik et al. Increased Akt signaling in the mosquito fat body increases adult survivorship. FASEB J

High Impact Journal from Malaria Portal - 31 December 2015 - 12:00am
Akt signaling regulates diverse physiologies in a wide range of organisms. . . .
Categories: malaria news feeds

JJ Campo et al. RTS,S vaccination is associated with serologic evidence of decreased exposure to Plasmodium falciparum liver and blood stage parasites. Mol Cell Proteomics

High Impact Journal from Malaria Portal - 30 December 2015 - 12:00am
The leading malaria vaccine candidate, RTS,S, targets the sporozoite and liver stages of the Plasmodium falciparum life cycle, yet it provides partial protection against disease associated with subsequent blood-stage of infection. . . .
Categories: malaria news feeds

C Waterman et al. Miniaturized Cultivation of Microbiota for Antimalarial Drug Discovery. Med Res Rev

High Impact Journal from Malaria Portal - 29 December 2015 - 12:00am
The ongoing search for effective antiplasmodial agents remains essential in the fight against malaria worldwide. . . .
Categories: malaria news feeds

CV Hobbs et al. Neither the HIV Protease Inhibitor Lopinavir-Ritonavir nor the Antimicrobial Trimethoprim-Sulfamethoxazole Prevent Malaria Relapse in Plasmodium cynomolgi-Infected Non-Human Primates. PLoS One

High Impact Journal from Malaria Portal - 27 December 2015 - 12:00am
Plasmodium vivax malaria causes significant morbidity and mortality worldwide, and only one drug is in clinical use that can kill the hypnozoites that cause P. . . .
Categories: malaria news feeds

K Schuldt et al. Endothelial protein C receptor gene variants not associated with severe malaria in ghanaian children. PLoS One

High Impact Journal from Malaria Portal - 27 December 2015 - 12:00am
Two recent reports have identified the Endothelial Protein C Receptor (EPCR) as a key molecule implicated in severe malaria pathology. . . .
Categories: malaria news feeds

M Asghar et al. Chronic infection. Hidden costs of infection: chronic malaria accelerates telomere degradation and senescence in wild birds. Science

High Impact Journal from Malaria Portal - 23 January 2015 - 12:00am
Recovery from infection is not always complete, and mild chronic infection may persist. . . .
Categories: malaria news feeds

Genetic architecture of artemisinin-resistant Plasmodium falciparum

CiteULike malaria tags - 22 January 2015 - 10:47am
Nature Genetics (19 January 2015), doi:10.1038/ng.3189
Olivo Miotto, Roberto Amato, Elizabeth Ashley, Bronwyn MacInnis, Jacob Almagro-Garcia, Chanaki Amaratunga, Pharath Lim, Daniel Mead, Samuel Oyola, Mehul Dhorda, Mallika Imwong, Charles Woodrow, Magnus Manske, Jim Stalker, Eleanor Drury, Susana Campino, Lucas Amenga-Etego, Thuy-Nhien Thanh, Hien Tran, Pascal Ringwald, Delia Bethell, Francois Nosten, Aung Phyo, Sasithon Pukrittayakamee, Kesinee Chotivanich, Char Chuor, Chea Nguon, Seila Suon, Sokunthea Sreng, Paul Newton, Mayfong Mayxay, Maniphone Khanthavong, Bouasy Hongvanthong, Ye Htut, Kay Han, Myat Kyaw, Md Faiz, Caterina Fanello, Marie Onyamboko, Olugbenga Mokuolu, Christopher Jacob, Shannon Takala-Harrison, Christopher Plowe, Nicholas Day, Arjen Dondorp, Chris Spencer, Gilean McVean, Rick Fairhurst, Nicholas White, Dominic Kwiatkowski
Categories: malaria news feeds

A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys

CiteULike malaria tags - 22 January 2015 - 10:02am
Cell Host & Microbe, Vol. 17, No. 1. (January 2015), pp. 130-139, doi:10.1016/j.chom.2014.11.017
Alexander Douglas, Christian Baldeviano, Carmen Lucas, Luis Lugo-Roman, Cécile Crosnier, Josefin Bartholdson, Ababacar Diouf, Kazutoyo Miura, Lynn Lambert, Julio Ventocilla, Karina Leiva, Kathryn Milne, Joseph Illingworth, Alexandra Spencer, Kathryn Hjerrild, Daniel Alanine, Alison Turner, Jeromy Moorhead, Kimberly Edgel, Yimin Wu, Carole Long, Gavin Wright, Andrés Lescano, Simon Draper
Categories: malaria news feeds

A Hardy et al. Mapping hotspots of malaria transmission from pre-existing hydrology, geology and geomorphology data in the pre-elimination context of Zanzibar, United Republic of Tanzania. Parasit Vectors

High Impact Journal from Malaria Portal - 22 January 2015 - 12:00am
BackgroundLarval source management strategies can play an important role in malaria elimination programmes, especially for tackling outdoor biting species and for eliminating parasite and vector populations when they are most vulnerable during the dry season. . . .
Categories: malaria news feeds

M Eisenhut et al. Vasospasm in cerebral inflammation. Int J Inflam

High Impact Journal from Malaria Portal - 22 January 2015 - 12:00am
All forms of cerebral inflammation as found in bacterial meningitis, cerebral malaria, brain injury, and subarachnoid haemorrhage have been associated with vasospasm of cerebral arteries and arterioles. . . .
Categories: malaria news feeds

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