The Synaptic Leap

Does praziquantel bind actin?

Tallima and El Ridi recently proposed actin as the molecular target of PZQ, based on affinity chromatography studies.

Todd and Cioli performed similar experiments (with a different support-bound PZQ) and found actin bound to PZQ-free support, implying that actin is a false positive, identified due to its cellular abundance.

Other evidence? Required projects?