The Synaptic Leap

This page details attempts to optimise the purification of praziquantel by chromatography, with an emphasis on preparative, rather than analytical, work. Anybody can add to/edit this page.
 
Literature
1. This paper describes the purification of enantiopure PZQ using "chloroform/methanol 0–0.3% MeOH as a solvent system."
2. This paper uses 1:1 EtOAc/petroleum ether ramping to pure EtOAc.
3. This paper uses "thick layer preparative chromatography [prep TLC] benzene/ethyl acetate 1/1, silica gel."