This last paper comes from the same group who recently published an extremely important Nature Medicine paper on the identification of oxadiazoles for the treatment of schisto.
There was also an important publication in Nature from a group including Novartis on the identification of new compounds for the treatment of drug-resistant nematodes, especially important for the treatment of livestock infections.
Comments
Some 2008 VIPs in Schisto
Several interesting recent articles in PLoS Neglected Diseases:
Research Agenda for schisto
A reply to this Research Agenda warning against complacency with PZQ
The exciting identification of inhibitors of thioredoxin/glutathione reductase (TGR) as leads in schisto chemotherapy
This last paper comes from the same group who recently published an extremely important Nature Medicine paper on the identification of oxadiazoles for the treatment of schisto.
There was also an important publication in Nature from a group including Novartis on the identification of new compounds for the treatment of drug-resistant nematodes, especially important for the treatment of livestock infections.
The NIH-NIAID Schistosomiasis Resource Center
A recent article in PLoS ND highlighting this essential resource for all those working (experimentally, biologically) in the schisto field.
New PZQ review article
Excellent summary of the bio and use of praziquantel just published, including possible replacements.