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Biological Results for ATP Series from April 2013

Published by MatTodd on 1 May 2013 - 3:48am

Subject 

Results

Comments on Latest Biological Results - April 2013

Data may be viewed here.
General page for the whole aminothienopyrmidine series is here.

The content of this post is also viewable on a Google+ post.

Biological Data

Published by MatTodd on 1 May 2013 - 3:39am

Subject 

Results

Chid pages to this one focus on biological evaluation in the GSK ATP project - results and the response to the results.

 

The GSK Aminothienopyrimidine (ATP) Series

Published by MatTodd on 1 May 2013 - 3:38am

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Results

The second strand of the open source drug discovery for malaria project involves aminothienopyrimidines (ATPs). The wiki summary page contains the current To Do list. Child pages to this one refer to specific aspects of the project.

26 Feb

Sulfonamides

Published by Matin

As I alluded to at the end of my previous entry, I've been working on a way to make sulfonamides of the arryl pyrrole series for the OSDD Malaria project.

 
 
 
 
 
 
Figure 1. Examples of sulfonamides that are currently being made for testing as anti-malarials.

02 Jan

Abridged Transcript of OSDD Open Meeting (17.12.12)

Published by Alice Williamson

Subject 

Results

+OSDD Malaria, @OSDDMalaria

Attendees:

Matthew Houghton Todd (MHT), University of Sydney, +Matthew Todd, @MatToddChem

Paul Willis (PW), Medicines for Malaria Venture, http://www.mmv.org/about-us/our-team/paul-willis

Murray N Robertson (MNR), University of Sydney, +Murray Robertson, @murrayfold

Alice E Williamson (AEW), University of Sydney, +Alice Williamson, @all_isee

Biological Results for Third Set of Compounds

Published by MatTodd on 15 December 2012 - 6:57am

Subject 

Results

A summary of the biological activities obtained for the third set of compounds in 2012 - those arising from the consultation for which synthetic and commercial compounds that were most wanted. See also some links for analysis of trends in the data.

First set (Oct 19th) Data, and these were discussed briefly in an online meeting.

10 Dec

Advice Needed: Generation of Analogues in the Thienopyrimidine Series

Published by JimCronshaw

Seasons greetings all. This is the December 2012 update from my side of the Todd lab. I have finished my honours project and submitted my thesis to obtain Hons I - which is highly pleasing - and I'm back for a period of time to assist the Todd group and their antimalarial project. Specifically, I hope to generate a variety of analogues of the hit compound within the aminothienopyrimidine series (Figure 1)

 

Open Source Drug Discovery for Malaria Project Meeting Oct 19th 2012

Published by MatTodd on 27 October 2012 - 11:24am

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Results

This meeting was the first of what will become regular monthly meetings for the OSDD malaria project. Open to all, so please feel free to come along to them.

Wiki pages:
Arylpyrroles
Thienos
Triazolos

Open Source Drug Discovery for Malaria Project Meetings

Published by MatTodd on 27 October 2012 - 11:13am

Subject 

Results

Project meetings for the Open Source Drug Discovery for Malaria project will be held in the public domain. Meetings will be linked below, with uploads to YouTube. Open to all interested.

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