Michael Wolfle

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TypeTitleAuthorRepliesLast updated
Book pagePictet-Spengler Route to (R)-PZQ MatTodd138 years 11 months ago
Book pageAsymmetric Hydrogenation of PZQ-enamide MatTodd119 years 4 months ago
Blog entryCleavage of the Cyclohexanoyl group of rac-PZQ Michael Wolfle29 years 7 months ago
Blog entryOptimizing the acid cleavage conditions II Michael Wolfle19 years 7 months ago
Book pageResolution of rac-Praziquanamine with quinic acid Michael Wolfle410 years 1 week ago
Blog entryOptimizing the acidic cleavage conditions of the cyclohexanoyl group of (rac)-PZQ Michael Wolfle310 years 1 month ago
Book pageResolution of Praziquanamine MatTodd1410 years 1 month ago
Book pageCatalyst screening for the Brønsted-catalysed Pictet-Spengler reaction to PZQ Michael Wolfle010 years 2 months ago
Book pageSynthesis of Cyclohexanoyl Chloride from Cyclohexane Carboxylic Acid Michael Wolfle210 years 5 months ago
Blog entryIn search for the acid-catalyzed Pictet-Spengler cyclisation using organic Brønsted acids Michael Wolfle010 years 6 months ago
Book pagePictet-Spengler route to rac-PZQ Michael Wolfle010 years 6 months ago
Book pageStarting Materials for the Synthesis of rac-PZQ Michael Wolfle110 years 6 months ago
Blog entryDerivatives of PZQ: 9,10-dimethoxy-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a] isoquinoline Michael Wolfle110 years 6 months ago
Blog entryPictet-Spengler approach to PZQ: Cyclisation to Praziquanamin Michael Wolfle310 years 6 months ago
Blog entryPictet-Spengler approach to PZQ: 2-((2,2-dimethoxyethyl)amino)-N-phenethylacetamide Michael Wolfle010 years 7 months ago
Blog entryPictet-Spengler approach to PZQ: 2-chloro-N-phenethylacetamide Michael Wolfle010 years 7 months ago
Blog entryCleavage experiment with PZQ using 50 vol% TFA Michael Wolfle010 years 8 months ago
Blog entryScreening approach to the Reissert reaction Michael Wolfle010 years 8 months ago
Blog entryRacemic synthesis of rac-PZQ via the Reissert route Michael Wolfle010 years 8 months ago
Book pageReissert Approach to rac-PZQ Michael Wolfle010 years 9 months ago